Salmonella: Products and markets

The incidence and economic costs of salmonellosis are on the increase. It is estimated that 81 million people become sick and 9,100 die from foodborne illnesses each year in the US.
Controlling salmonella is a major undertaking. This report investigates the prevalence of the disease and focuses on the products used for its prevention, diagnosis and treatment.

Salmonella: Products and markets answers the following questions:

This report is essential reading for all those involved in the production of salmonella diagnosis, prevention and control products, as well as managers in government agencies, pressure groups and other affected industries.

PUBLISHED: JANUARY 2000
REF: SR187E
PAGES: 102
PRICE: £295/$620/¥71,000

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CONTENTS
LIST OF TABLES
LIST OF FIGURES
ABBREVIATIONS


CHAPTER 1 INTRODUCTION
1.1 Basic classification
1.2 Salmonellosis in humans
1.2.1 Clinical types of disease
1.2.2 Infective dose and incubation period
1.2.3 Pathogenesis
1.2.4 Serotypes of salmonella
1.2.5 Morbidity
1.2.6 Sequelae
1.2.7 Excretion
1.2.8 Treatment
1.3 Salmonellosis in animals
1.3.1 Transmission and incubation period
1.3.2 Pathogenesis
1.3.3 Clinical signs
1.3.4 Excretion
1.3.5 Serotypes
1.3.6 Animal species
1.3.6.1 Cattle
1.3.6.2 Sheep
1.3.6.3 Pigs
1.3.6.4 Poultry
1.3.6.5 Horses
1.3.6.6 Aquatic species
1.4 Sources of infection
1.4.1 To animals
1.4.2 To humans
1.4.2.1 Contaminated foodstuffs
1.5 Economic cost
1.5.1 Economic cost in humans
1.5.2 Economic cost in animals


CHAPTER 2 THE PATHOGENS AND THEIR GLOBAL INCIDENCE
2.1 Humans
2.1.1 Europe
2.1.1.1 Enter-net
2.1.1.2 England and Wales
2.1.1.3 Czech Republic and MDR S. typhimurium DT104
2.1.2 US
2.1.3 Other regions
2.1.3.1 Latin America and the Caribbean
2.1.3.2 Japan
2.2 Animals
2.2.1 Europe
2.2.1.1 Feed stuffs
2.2.1.2 Poultry
2.2.1.3 Pigs
2.2.1.4 Cattle
2.2.1.5 Sheep and goats
2.2.1.6 Food
2.2.1.7 Antibiotic resistance
2.2.2 US
2.2.2.1 Animals
2.2.2.2 Food
2.2.3 Other regions


CHAPTER 3 THE REGULATORY ENVIRONMENT
3.1 Worldwide
3.2 Europe
3.2.1 Zoonoses
3.2.1.1 Poultry
3.2.1.2 Pigs
3.2.1.3 Cattle
3.2.1.4 Feed stuffs
3.2.2 Growth promoters
3.2.3 Antimicrobial resistance
3.3 US
3.3.1 National Poultry Improvement Plan
3.3.2 PulseNet
3.3.3 Antimicrobials
3.3.4 Food safety
3.3.4.1 Eggs
3.3.4.2 Meat plants
3.3.4.3 Imports
3.3.5 Vaccines
3.3.6 Funding
3.4 Other regions
3.4.1 Latin America and the Caribbean
3.4.2 Argentina
3.4.3 Kuwait
3.4.4 Australia


CHAPTER 4 SALMONELLA DIAGNOSIS AND CONTROL
4.1 Diagnostics
4.1.1 Microbe testing
4.1.2 Animal testing
4.2 Therapeutics
4.2.1 Antimicrobials
4.2.1.1 Penicillins
4.2.1.2 Cephalosporins
4.2.1.3 Chloramphenicol
4.2.1.4 Aminoglycosides
4.2.1.5 Sulphonamides
4.2.1.6 Tetracyclines
4.2.1.7 Fluoroquinolones
4.2.2 Fluid therapy
4.3 Prophylactics
4.3.1 Preempt
4.3.2 Protect
4.3.3 Aviguard
4.3.4 Vitacid
4.3.5 Cellulac
4.4 Vaccines and antisera
4.4.1 Vaccines
4.4.1.1 Poultry
4.4.1.2 Cattle
4.4.1.3 Sheep
4.4.1.4 Pigs
4.4.2 Antiserum
4.5 Environmental treatments


CHAPTER 5 MARKETS FOR SALMONELLA PRODUCTS
5.1 Animal health market
5.2 Geographical markets
5.3 Species
5.3.1 Cattle
5.3.2 Sheep and goats
5.3.3 Pigs
5.3.4 Poultry
5.3.5 Companion animals
5.4 Products
5.4.1 Antibiotics
5.4.2 Vaccines
5.4.3 Feed stuff control
5.4.4 Competitive exclusion products
5.4.5 Environmental control
5.5 Diagnostics
5.5.1 Animal and environmental testing
5.5.2 Testing of meat products
5.6 Genetic resistance


CHAPTER 6 COMPANY PROFILES
6.1 Agener
6.2 Bayer
6.3 Boehringer Ingelheim
6.4 Daiichi
6.5 Dainippon
6.6 Elanco
6.7 Impstoffwerk Dessau-Tornau
6.8 Fort Dodge
6.9 Hoechst Roussel Vet
6.10 Hoffmann-La Roche
6.11 IDEXX
6.12 Intervet
6.13 Merial
6.14 Neogen
6.15 Qualicon
6.16 Pfizer
6.17 Pharmacia & Upjohn
6.18 Sanofi
6.19 Schering-Plough Animal Health


REFERENCES

LIST OF TABLES
Table 1.1 Important Salmonella species in livestock
Table 1.2 Number of isolates coming from animal and food sources

Table 2.1 Number of cases of Salmonellosis in humans in the EU, 1995-1997
Table 2.2 International outbreaks recognised and investigated by Enter-Net/Salm-Net, 1996-1997
Table 2.3 Number of persons affected with salmonella food poisoning in Japan, 1994-1997
Table 2.4 Number of salmonella isolates in animal-derived feed materials within the countries of the EU, 1997
Table 2.5 Number of salmonella isolates in vegetable-derived feed materials within the countries of the EU, 1997
Table 2.6 Incidence of important Salmonella species in birds other than chickens in the UK, 1997
Table 2.7 Percentage incidence of contaminated carcasses and number of plants complying in the US, 1998

Table 4.1 Antibacterial agents active against salmonella

Table 5.1 World animal health market value, 1991-1998
Table 5.2 Segmentation of the world animal health market, 1998
Table 5.3 World animal health market structure by major product sector, 1998

Table 6.1 Pfizer animal health sales by product sector, 1998
Table 6.2 Schering-Plough Animal Health sales by region, 1998

LIST OF FIGURES
Figure 1.1 Clinical signs associated with human salmonellosis
Figure 1.2 Percentage of isolates coming from animal and food sources
Figure 2.1 Incidence rates of Salmonellosis in humans in the EU, 1995-1998
Figure 2.2 Number of reported cases of S. enteritidis in the EU, 1995-1998
Figure 2.3 Percentage of S. enteritidis of all reported cases of salmonellosis in EU countries, 1995-1997
Figure 2.4 Percentage of S. typhimurium of all reported cases of salmonellosis in EU countries, 1995-1997
Figure 2.5 Number of reported cases of salmonella in humans in England and Wales, 1981 and 1990-1998
Figure 2.6 Salmonella serotypes in feed materials and feed stuffs, 1997,
Figure 2.7 Percentage incidence of salmonella in breeding flocks in EU member countries, 1995-1997
Figure 2.8 Percentage incidence of salmonella in layer breeder and layer flocks in EU member countries, 1997
Figure 2.9 Incidence of salmonella in broiler breeder and broiler flocks in EU member countries, 1997
Figure 2.10 Main serotypes in pigs and pork in a number of European countries, 1997
Figure 2.11 Number of outbreaks of total and important Salmonella species in Northern Ireland, 1996-1997
Figure 5.1 Percentage of global sales for all animal health products by species, 1998
Figure 5.2 Percentage shares of the world animal health market by major product sector, 1998

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